Macau, China – Jose Souza, the promising Brazilian welterweight, is set to make his long-awaited Ultimate Fighting Championship (UFC) debut on Saturday’s Fight Night show in Macau, China, almost three years after first signing with the promotion. His journey to the octagon has been anything but conventional, marked by a significant doping suspension that derailed his initial aspirations and forced him onto a challenging path of introspection and perseverance. Souza, also known by his birth name Jose Henrique, will face fellow UFC newcomer Ding Meng, a seasoned Chinese veteran boasting a professional record of 35 wins and 9 losses.
Souza’s initial signing with the UFC in 2023 was a dream realized, swiftly followed by a nightmare. His life took an unexpected turn after a positive drug test in March 2023, which detected two metabolites of the anabolic agent nandrolone. This violation of the UFC Anti-Doping Policy, then administered by the United States Anti-Doping Agency (USADA), led to a two-year suspension, effectively putting his burgeoning career on hold. The news sent shockwaves through the young fighter’s world, plunging him into a period of profound uncertainty and mental struggle.
"It was really difficult," Souza candidly told MMA Fighting, reflecting on the arduous period. "I went through a lot of difficulties, a lot of bad thoughts, even thinking that I might never be able to fight in the UFC, but that only gave me more strength. It gave me the motivation to think, ‘I want to be there again, and I’m going to make it happen.’ And I did." During his forced hiatus, Souza committed himself to relentless training and self-improvement, using the setback as a catalyst for growth. "I spent that time away working, waiting, training, giving my best every single day. That’s what gave me the strength to keep going, because I needed a goal, and my goal was to make it to the UFC."
Souza vehemently denies ever intentionally taking illegal substances to enhance his performance. He asserts that the positive test stemmed from a medical recommendation made under specific circumstances. The incident traces back to August 2022 when Souza competed on Dana White’s Contender Series (DWCS), a crucial platform for aspiring fighters to earn a UFC contract. Despite losing a decision on the show, his performance caught the eye of UFC President Dana White and matchmaker Sean Shelby, who reportedly told him, "We like you. Go get a few fights outside and we’ll bring you into the promotion." Souza underwent drug testing during his DWCS appearance and passed without any issues, reinforcing his claim of being clean. "I was clean, I had never taken anything. That’s the truth, I had never taken anything," he stated.
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Following his Contender Series fight, Souza prepared for a return to the Shooto Brasil cage in February 2023. It was during this training camp, approximately two to three weeks before his scheduled bout, that he sustained a knee injury while wrestling. Seeking medical attention, Souza consulted a doctor who, according to the fighter, advised him to use Deca-Durabolin, a brand name for nandrolone decanoate. Nandrolone is an anabolic androgenic steroid, typically used to promote muscle growth, increase bone density, and aid in recovery from injuries. It is a prohibited substance under nearly all major sports anti-doping policies due to its performance-enhancing properties.
Souza recounted the doctor’s specific advice: "I went to the doctor and he told me, ‘You don’t fight in promotions with drug testing so let’s use this medication.’ That’s when he recommended Deca-Durabolin to me, something used post-surgery that works very quickly. That was it." This advice proved to be critically flawed. While some regional promotions may not conduct comprehensive drug testing for every fighter on every card, Shooto Brasil is sanctioned by the Brazilian MMA Athletic Commission (CABMMA), which does have anti-doping protocols in place. Souza’s doctor’s assumption about the absence of testing was incorrect and ultimately led to his downfall.
After receiving the injection, Souza competed at Shooto Brasil, securing a knockout victory that further solidified his appeal to the UFC. His manager, Andre Pederneiras, affectionately known as ‘Dede’, immediately contacted Sean Shelby, relaying the impressive performance. "Right there, when I got out of the cage, ‘Dede’ said, ‘You just signed with the UFC.’ It was that whole emotional post-fight moment," Souza recalled. The elation was short-lived. Shortly after his Shooto Brasil fight, Souza traveled to Russia with a friend who was fighting in the ACA promotion. On March 8, 2023, USADA officials arrived to conduct a drug test, a standard procedure for newly signed UFC athletes.
Souza admitted to a critical error in judgment: he did not disclose his use of Deca-Durabolin upon signing with the UFC or during the USADA testing process. "I didn’t tell Dede [about the use] and that was my mistake," Souza confessed. "The blame is completely mine, I put all of it on my shoulders because I could have talked to him beforehand and he would have guided me toward better options. But I was thinking, ‘I want to fight, I need to fight, these guys are watching me.’ And that was it." He explained that his decision not to disclose was based on the doctor’s assurance that the substance would be out of his system within seven days, a timeframe that proved to be inaccurate for nandrolone metabolites.
When confronted with the positive test results, Souza found himself in a precarious position. The doctor who had recommended Deca-Durabolin "didn’t want to get involved" in his defense before USADA. With limited options and acknowledging his oversight, Souza accepted the two-year suspension. This ban meant that he would be ineligible to compete in any UFC-sanctioned events until March 2025. The impact on a young fighter, whose career momentum relies heavily on consistent activity, was immense.
Despite the ban from UFC-affiliated competitions, Souza was determined to stay active and maintain his competitive edge. During his suspension, he sought opportunities in promotions that did not adhere to USADA’s bans. In 2024, he competed in a boxing match, defeating UFC veteran Leonardo Guimaraes. Months later, he secured back-to-back victories under the Centurion FC banner, a promotion known for hosting fights outside the direct purview of major anti-doping agencies. These fights were crucial for Souza, allowing him to refine his skills, gain valuable experience, and demonstrate his continued commitment to fighting.
Crucially, the UFC had kept a watchful eye on Souza. "They had given me their word that after that year they would bring me back, and that’s exactly what they did," Souza revealed. "They honored their word, and now I’m back. And you can be sure that I’ll be ready to show why I deserve to be in the UFC." This commitment from the UFC underscores their belief in Souza’s talent and potential, despite the doping infraction. After his suspension ended in March 2025 and following his active period in other promotions, Souza earned his call back to the UFC in 2026, leading directly to his Macau debut.
His path to this specific fight in Macau was also fraught with challenges. The 24-year-old Nova Uniao fighter faced multiple matchup cancellations earlier in 2026, including potential bouts against Eric Nolan, Nikolay Veretennikov, and Charles Radtke. The constant changes in opponents can be mentally taxing for any fighter, requiring adaptability and resilience. Ultimately, he agreed to face Ding Meng, a formidable opponent with an extensive record, on what is essentially enemy territory for the Brazilian.
Reflecting on his journey, Souza believes the entire ordeal has been a transformative experience. "I learned a lot from it all," Souza affirmed. "I needed to go through that. The first time I signed with the UFC, I don’t think I was ready. I was a very young kid, I had no real experience in life. I learned a lot from fighting on the Contender Series, but I still had a lot of maturing to do as a person and as an athlete. Today, I’m sure that I’m much more prepared to be a UFC fighter."
Souza’s debut in Macau represents more than just another fight; it is the culmination of a redemption arc, a testament to his resilience, and a definitive statement of his maturity. Stepping into the octagon against a veteran like Ding Meng, Souza will aim to validate the UFC’s faith in him and prove that he is now, truly, ready for the biggest stage in mixed martial arts.
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