Ali Akbar RosadyNew York City’s iconic Madison Square Garden is set to host a pivotal night of mixed martial arts on Saturday, as UFC 322 features a highly anticipated welterweight championship showdown between reigning titleholder Jack Della Maddalena and the formidable Islam Makhachev. Della Maddalena, who captured the UFC welterweight championship in his last outing by defeating Belal Muhammad at UFC 315 this past May, faces a significant challenge in Makhachev, who makes his welterweight debut following an impressive 15-bout winning streak in the lightweight division. The main card proceedings are scheduled to commence at 10 p.m. ET, preceded by the preliminary bouts at 8 p.m. ET and the early preliminaries kicking off at 6 p.m. ET.
Makhachev enters the Octagon as the favorite in the latest UFC 322 odds provided by DraftKings Sportsbook, listed at -298 (requiring a $298 wager to yield a $100 profit). Champion Della Maddalena, conversely, is positioned as the underdog at +240. The co-main event promises another championship spectacle, with Valentina Shevchenko, the defending women’s flyweight champion, holding favorite status at -148 against challenger Zhang Weili, who stands at +124. For those seeking informed analysis on these and other matchups, detailed MMA predictions and betting advice are available from SportsLine expert Daniel Vithlani.
Vithlani has established himself as a prominent and consistently successful UFC analyst since his SportsLine debut in January 2023, where he posted a flawless 5-0 record for UFC 283. His main-card sports betting picks have collectively generated over $1,500 in profits for his followers. Notable successes include accurately predicting an upset victory for Sean O’Malley (+210) against then-champion Aljamain Sterling (-250) at UFC 292, contributing to a 4-1 main card performance. His UFC 299 selections also featured successful underdog calls on Dustin Poirier (+190) over Benoit Saint Denis (-230) and Michael Page (+110) against Kevin Holland (-130).
Jack Della Maddalena, 29, has demonstrated remarkable resilience and skill since his professional debut in March 2016. Despite losing his initial two fights, he has remained undefeated since, embarking on a dominant run. His entry into the UFC was solidified with a unanimous decision victory over Ange Loosa in Dana White’s Contender Series 39 in September 2021. He made an immediate impact in his UFC debut at UFC 270 in January 2022, securing a TKO win over Pete Rodriguez. Della Maddalena’s professional record stands at 18-2, featuring 12 victories by knockout, two by submission, and four by decision, highlighting his versatile finishing capabilities.
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His meteoric rise has been recognized with significant accolades, including ESPN’s 2022 UFC Men’s Rookie of the Year and Cageside Press’s 2022 Co-Newcomer of the Year alongside Jailton Almeida. UFC.com also named him their 2022 Newcomer of the Year. Della Maddalena has consistently delivered exciting performances, earning four Performance of the Night bonuses and two Fight of the Night honors. His current standing as No. 8 in the UFC men’s pound-for-pound rankings underscores his elite status within the sport.
Islam Makhachev, 34, initiated his professional career in August 2010, quickly amassing 12 consecutive victories, including his UFC debut in May 2015 with a submission win over Leo Kuntz at UFC 187. His sole professional defeat occurred later that year, a knockout loss to Adriano Martins. Since then, Makhachev has embarked on an extraordinary 15-bout winning streak, establishing himself as one of the most dominant forces in MMA. His comprehensive record of 27-1 includes five knockout wins, 13 submissions, and nine decisions, showcasing his well-rounded skill set, deeply rooted in Sambo and high-level grappling.
Makhachev is a former UFC lightweight champion, successfully defending his title on four occasions before announcing his move to the welterweight division. His performances have garnered three Fight of the Night awards and three Performance of the Night bonuses. He holds the record for the most UFC lightweight title wins with five (including his initial championship victory) and is tied for the second-longest win streak in UFC history at 15 bouts, alongside former welterweight king Kamaru Usman. His transition to welterweight presents a compelling narrative, testing his grappling and striking against naturally larger opponents. The stylistic clash with Della Maddalena, a powerful and precise striker, sets the stage for a classic striker-versus-grappler encounter.
Beyond the main event, the co-main event between Valentina Shevchenko and Zhang Weili is poised to deliver a high-stakes women’s flyweight championship bout. Shevchenko, known for her surgical striking and strong grappling, aims to solidify her legacy against the dynamic and aggressive striking of Zhang Weili, a former strawweight champion looking to claim a second UFC title in a different weight class. This fight pits two elite female athletes with contrasting styles, promising a tactical and explosive contest.
The main card also features several other intriguing matchups. Sean Brady (-142) is slated to face Michael Morales (+120) in a welterweight clash. Brady, an undefeated grappler, seeks to continue his ascent against the dangerous striking and finishing ability of Morales. Another welterweight bout sees Leon Edwards (+140) against Carlos Prates (-166). Both fighters will be looking to make a statement and climb the competitive welterweight ladder. The lightweight division will also be showcased with Beniel Dariush (+160) taking on Benoit Saint-Denis (-192). Dariush, a veteran with a deep grappling and striking arsenal, faces the relentless pressure and powerful attacks of Saint-Denis, in a fight that could have significant implications for the lightweight rankings.
Ahead of the event, Daniel Vithlani has provided an early prediction for the featherweight matchup between Chepe Mariscal (-102) and Pat Sabatini (-118) on the early preliminary card. Vithlani favors Mariscal to secure a slight upset. "Mariscal is now 5-0 in the UFC and hasn’t lost a fight since 2020," Vithlani stated to SportsLine. "He is a scrappy fighter who welcomes a nasty affair. Mariscal uses his pace, pressure and grittiness to intimidate his opponents and wear on them. His volume-striking attack makes him dangerous, but it’s his ability to grapple and scramble that give him the edge in this matchup. Sabatini is a Ju-Jitsu ace, with 13 of his 19 pro wins coming by submission. He is a savvy grappler who can keep his opponents pinned to the mat. However, I have a hard time seeing him do that to Mariscal, who has never been submitted in his 18-6 pro career. Mariscal has a 73% takedown defense rate and has shown the ability to get up when taken down. If this fight plays out on the feet, Mariscal’s relentlessness will overwhelm Sabatini."
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Vithlani’s comprehensive analysis extends to the Della Maddalena vs. Makhachev main event and other crucial bouts on the UFC 322 card. He has identified another fighter whose "constant barrage of strikes and takedowns" is predicted to lead to a significant victory. His full slate of betting picks and detailed analysis for UFC 322 are exclusively available through SportsLine.
The full UFC 322 main fight card and associated odds (subject to change) are as follows:
- Jack Della Maddalena (+240) vs. Islam Makhachev (-298) – UFC Welterweight Championship
- Valentina Shevchenko (-148) vs. Zhang Weili (+124) – Women’s Flyweight Championship
- Sean Brady (-142) vs. Michael Morales (+120) – Welterweight Bout
- Leon Edwards (+140) vs. Carlos Prates (-166) – Welterweight Bout
- Beniel Dariush (+160) vs. Benoit Saint-Denis (-192) – Lightweight Bout
UFC 322 is set to be a night of high-stakes action, crowning new champions or solidifying existing reigns, and further shaping the landscape of multiple divisions within the Ultimate Fighting Championship.
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