Ali Akbar Rosady
The Ultimate Fighting Championship (UFC) heavyweight division is poised for a monumental showdown this Saturday, October 25, 2025, as reigning champion Tom Aspinall prepares to defend his undisputed title against the formidable No. 1 contender, Ciryl Gane, at UFC 321: Aspinall vs. Gane. The highly anticipated event will unfold at the state-of-the-art Etihad Arena on Yas Island/Yas West, United Arab Emirates, with the main card commencing at 2 p.m. ET, following the preliminary bouts which begin at 10 a.m. ET.
Tom Aspinall, a dynamic force in the heavyweight landscape, ascended to the interim UFC heavyweight championship in November 2023 with a decisive knockout victory over Sergei Pavlovich at UFC 295. His dominance continued into July 2024, where he successfully defended his interim title by dispatching Curtis Blaydes via knockout at UFC 304. Aspinall’s impressive performances led to his promotion to undisputed champion on June 21, 2025, solidifying his position at the pinnacle of the heavyweight division. The 32-year-old British fighter enters this contest with significant momentum, having secured 11 wins in his last 12 outings, including the redemption victory over Blaydes, who had previously handed Aspinall a loss at UFC Fight Night: Blaydes vs. Aspinall in July 2022.
Aspinall’s professional mixed martial arts journey began in December 2014 in Manchester, England, culminating in his UFC debut in July 2020. Throughout his career, he has amassed a remarkable record of 15-3, with 12 victories coming by knockout and three by submission, showcasing his diverse and lethal skill set. Aspinall’s impactful presence in the octagon has been consistently recognized, earning him Performance of the Night honors an impressive seven times, a feat that places him tied for fourth-most in UFC history. His fights are often characterized by their brevity and intensity; he holds the record for the shortest average fight time in UFC history at a mere 2 minutes and 2 seconds. Furthermore, his aggressive striking is evident in his rate of 4.09 knockdowns per 15 minutes, ranking him second all-time in that metric. His burgeoning career has also seen him recognized as ninth for UFC Newcomer of the Year in 2020 and securing the No. 3 spot for UFC Submission of the Year in 2022. The year 2024 proved particularly fruitful for Aspinall, as he garnered two prestigious MMA awards: Breakthrough Fighter of the Year and Comeback of the Year.
Challenging Aspinall for the heavyweight crown is Ciryl Gane, the 35-year-old French contender hailing from Paris. Gane’s professional career commenced in August 2018, where he quickly made an impression with three consecutive knockout victories, catching the attention of UFC brass. He made his promotional debut in August 2019, securing a submission win over Raphael Pessoa at UFC Fight Night: Shevchenko vs. Carmouche 2. Gane embarked on an impressive undefeated streak, winning his first 10 professional fights, a run that included a third-round knockout of Derrick Lewis to capture the interim UFC heavyweight championship and Performance of the Night honors in August 2021.
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Gane brings a professional record of 13-2 into this championship bout. His victories are distributed across six knockouts, three submissions, and four decisions, highlighting his well-rounded offensive capabilities and strategic approach. His contributions to the sport have been acknowledged through various accolades, including being ranked as the UFC second-ranked Newcomer of the Year in 2019 and the No. 3 Fighter of the Year in 2021. In 2022, his thrilling third-round knockout of Tai Tuivasa at UFC Fight Night: Gane vs. Tuivasa was recognized as the seventh-ranked Fight of the Year. Gane enters this championship challenge following a split decision victory over Alexander Volkov at UFC 310 last December, demonstrating his ability to secure wins even in closely contested encounters.
Betting Odds and Expert Insights
The latest UFC 321 odds from DraftKings Sportsbook position Tom Aspinall as the favorite, currently listed at -345 (requiring a $345 risk to win $100). Ciryl Gane, in contrast, enters the bout as the underdog at +275. For new users interested in exploring betting opportunities, the DraftKings promo code offers a potential $300 in bonus bets if their initial wager wins, alongside three months of NBA League Pass.
For those seeking expert analysis and betting predictions, SportsLine’s highly-analytical UFC bettor, Daniel Vithlani, has provided his insights for UFC 321. Vithlani has established a strong track record since his debut in January 2023, notably starting with a 5-0 record for UFC 283 and accumulating over $1,500 in profit on his UFC main-card picks. His past successes include accurately predicting an upset victory for Sean O’Malley (+210) against Aljamain Sterling (-250) at UFC 292 as part of a 4-1 main card. Vithlani’s picks for UFC 299 also featured successful underdog selections on Dustin Poirier (+190) against Benoit Saint Denis (-230) and Michael Page (+110) against Kevin Holland (-130).
Vithlani has thoroughly analyzed the Tom Aspinall vs. Ciryl Gane main event and other significant matchups on the card. Among his disclosed preliminary card selections is a pick for Jose Delgado (-155) to defeat Nathaniel Wood (+130) in a featherweight contest scheduled for approximately 11:45 a.m. ET.
Elaborating on his pick, Vithlani stated, "Delgado is a rising featherweight prospect who looks to be legitimate. Training out of the MMA Lab gym, Delgado is a rangy and explosive striker who throws nasty knees and elbows. In his last fight, Delgado knocked out a fighter with great durability in under 30 seconds. Standing 5-foot-11 with a 73-inch reach, Delgado is big for the weight class and will have a considerable size advantage. Wood is a tactical kickboxer with strong UFC experience, and he will provide a step-up in competition for Delgado. However, I don’t think he’ll be able to outpoint Delgado for three rounds. Delgado is the more dangerous and aggressive fighter, and he’s never been finished in his young 10-1 pro career. I think Delgado’s size and pressure will win him this fight." This pick is available at FanDuel, where new users can also explore the latest FanDuel promo code to potentially receive $300 in bonus bets instantly if their initial $5 bet wins.
Additionally, new users can consider the Underdog promo code, which offers $100 in site credits when playing $5 with the promo code CBSSPORTS2 in select states.
Co-Main Event and Undercard Highlights
The co-main event features a compelling women’s strawweight championship bout between Mackenzie Dern and Virna Jandiroba. Dern enters as the -148 favorite, while Jandiroba is listed at +124. This matchup promises a clash of grappling prowess and striking ability, with both fighters aiming to solidify their standing in the competitive strawweight division.
The full main card for UFC 321, with current odds, includes:
- Tom Aspinall (-345) vs. Ciryl Gane (+275) – UFC Heavyweight Championship
- Virna Jandiroba (+124) vs. Mackenzie Dern (-148) – Women’s Strawweight Championship
- Umar Nurmagomedov (-625) vs. Mario Bautista (+455) – Bantamweight Bout
- Alexander Volkov (+164) vs. Jailton Almeida (-198) – Heavyweight Bout
- Aleksandar Rakic (-118) vs. Azamat Murzakanov (-102) – Light Heavyweight Bout
Vithlani’s full range of picks, including his prediction for a fighter who "will use a physicality and wrestling edge" to secure a significant victory, are available through SportsLine. The event promises a night of high-stakes action across multiple divisions, culminating in the undisputed heavyweight championship bout.
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