The ultimate prize in mixed martial arts, the UFC heavyweight championship, will be fiercely contested this Saturday as reigning champion Tom Aspinall steps into the octagon against the formidable No. 1 contender Ciryl Gane at UFC 321: Aspinall vs. Gane. This highly anticipated bout will unfold at the prestigious Etihad Arena, located on Yas Island/Yas West in the United Arab Emirates, an increasingly popular destination for major UFC events. The main card is scheduled to commence at 2 p.m. ET, following the preliminary bouts which will kick off earlier at 10 a.m. ET.
Tom Aspinall’s ascent to the undisputed heavyweight throne has been marked by a series of dominant performances. The British powerhouse initially claimed the interim UFC heavyweight championship with a decisive knockout victory over Sergei Pavlovich at UFC 295 in November 2023. He then successfully defended this interim title by stopping Curtis Blaydes via knockout at UFC 304 in July 2024, avenging a previous loss. His exceptional run led to his promotion to undisputed champion on June 21, 2025, solidifying his status at the pinnacle of the heavyweight division. Across the octagon, Ciryl Gane, a former interim champion himself, enters this title eliminator fresh off a split decision win against Alexander Volkov at UFC 310 last December, a victory that re-established his claim as a top contender.
Betting Landscape: Aspinall Favored, Gane Underdog
Ahead of the monumental showdown, oddsmakers at DraftKings Sportsbook have positioned Tom Aspinall as the clear favorite, with odds currently set at -345. This implies a bettor would need to risk $345 to win $100 on an Aspinall victory. Conversely, Ciryl Gane is listed as the underdog at +275, meaning a $100 wager on Gane could yield a $275 profit if he pulls off the upset. The odds reflect Aspinall’s recent form and devastating finishing ability.
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The co-main event promises another high-stakes clash, this time for the women’s strawweight championship, featuring Mackenzie Dern as the -148 favorite against Virna Jandiroba, who is listed at +124. This bout adds another layer of intrigue to an already stacked fight card, with both fighters known for their grappling prowess and relentless pressure. For those looking to place wagers on these and other matchups, it is crucial to consider expert analysis.
Expert Insights from Daniel Vithlani
SportsLine expert Daniel Vithlani, a highly-analytical UFC bettor, has released his comprehensive predictions and betting advice for UFC 321. Vithlani has consistently delivered winning picks for SportsLine members since his debut in January 2023, notably starting with an impressive 5-0 record for UFC 283. His astute insights have resulted in over $1,500 in profit on his UFC main-card sports betting picks.
Vithlani’s track record includes accurately calling significant upsets, such as Sean O’Malley’s (+210) victory over Aljamain Sterling (-250) at UFC 292, a performance that contributed to a successful 4-1 main card. He also demonstrated his predictive acumen at UFC 299, where he picked underdog selections Dustin Poirier (+190) against Benoit Saint Denis (-230) and Michael Page (+110) against Kevin Holland (-130), both of which hit. Bettors who have followed his guidance on sportsbooks and betting apps have seen substantial returns.
Promotional Opportunities for New Users
New users keen on exploring betting opportunities for UFC 321 can take advantage of the DraftKings promo code, which offers $300 in bonus bets if their initial wager wins, plus an additional three months of NBA League Pass. Another option is the Underdog promo code, CBSSPORTS2, providing $100 in site credits when playing $5 in select states. These promotions offer attractive entry points for engaging with the event.
Vithlani has meticulously analyzed the Aspinall vs. Gane matchup from every conceivable angle, revealing his top betting picks and best bets. His full breakdown, along with predictions for other fights on the card, is available exclusively at SportsLine.
Fighter Profile: Tom Aspinall – The Rapid Finisher
At 32 years old, Tom Aspinall (15-3 overall, 12 KOs, 3 submissions) has established himself as one of the most exciting and efficient heavyweights in the UFC. His professional career, which began in December 2014 in Manchester, England, saw him make his UFC debut in July 2020. Aspinall’s record of 11 wins in his last 12 bouts underscores his exceptional form, highlighted by his recent knockout victory over Curtis Blaydes, which served as a crucial redemption after an injury-induced loss to Blaydes in July 2022.
Aspinall’s fighting style is characterized by remarkable speed and athleticism for a heavyweight, combined with devastating knockout power and a surprisingly potent ground game. His achievements extend beyond his title wins; he has earned Performance of the Night honors an astounding seven times, tying him for the fourth-most in UFC history. Furthermore, Aspinall boasts the shortest average fight time in UFC history at a mere 2 minutes and 2 seconds, a testament to his explosive finishing ability. His rate of 4.09 knockdowns per 15 minutes is the second-highest in the promotion, showcasing his constant threat. His impactful 2024 campaign saw him recognized with two MMA awards: Breakthrough Fighter of the Year and Comeback of the Year, further cementing his status as a dominant force.
Fighter Profile: Ciryl Gane – The Technical Striker
Ciryl Gane, 35, hailing from Paris, France, brings a different but equally dangerous skill set to the heavyweight division. "Bon Gamin" began his professional fighting career in August 2018, quickly making a name for himself with knockout wins in his first three bouts, which swiftly caught the attention of the UFC. He made his promotional debut in August 2019, securing a submission win over Raphael Pessoa at UFC Fight Night: Shevchenko vs. Carmouche 2. Gane’s initial run was flawless, as he stormed to a 10-0 record, culminating in a third-round knockout of Derrick Lewis to capture the interim UFC heavyweight championship and Performance of the Night honors in August 2021.
With a professional record of 13-2 (6 KOs, 3 submissions, 4 decisions), Gane is known for his fluid, technical striking, exceptional movement, and intelligent fight IQ, often described as a light-heavyweight trapped in a heavyweight’s body. He prefers to outpoint and outmaneuver his opponents, utilizing a high volume of strikes and evasive footwork. Gane was recognized as the UFC’s second-ranked Newcomer of the Year in 2019 and the No. 3 Fighter of the Year in 2021. His thrilling third-round knockout of Tai Tuivasa at UFC Fight Night: Gane vs. Tuivasa in 2022 earned him the seventh-ranked Fight of the Year distinction, demonstrating his capability to engage in exciting, high-level contests.
UFC 321 Preliminary Card Highlight: Delgado vs. Wood
Beyond the main attractions, the preliminary card also features compelling matchups, including a featherweight showdown between Jose Delgado (-155) and Nathaniel Wood (+130), slated for approximately 11:45 a.m. ET. Daniel Vithlani has identified this as a key fight, predicting a victory for Delgado.
According to Vithlani, "Delgado is a rising featherweight prospect who looks to be legit." Training out of the renowned MMA Lab gym, Delgado is characterized as a "rangy and explosive striker who throws nasty knees and elbows." His last fight saw him knock out a fighter known for his durability in under 30 seconds, signaling his immense power. Standing 5-foot-11 with a 73-inch reach, Delgado possesses a considerable size advantage for the featherweight division. While Wood is a "tactical kickboxer with strong UFC experience" who will present a step up in competition, Vithlani believes he "won’t be able to outpoint Delgado for three rounds." He further states, "Delgado is the more dangerous and aggressive fighter, and he’s never been finished in his young 10-1 pro career. I think Delgado’s size and pressure will win him this fight."
Bettors interested in this specific pick can place their wagers at FanDuel, where new users can also take advantage of the latest FanDuel promo code to get $300 in bonus bets instantly if their initial $5 bet wins.
Main Card Overview and Further Predictions
The UFC 321 main card is packed with other significant matchups that could shape their respective divisions:
- Umar Nurmagomedov (-625) vs. Mario Bautista (+455): A bantamweight clash featuring the highly touted and undefeated Nurmagomedov against a dangerous veteran in Bautista. Nurmagomedov’s dominant wrestling and striking make him a heavy favorite.
- Alexander Volkov (+164) vs. Jailton Almeida (-198): A heavyweight encounter between the veteran striker Volkov and the surging grappler Almeida. This promises a classic striker vs. grappler dynamic.
- Aleksandar Rakic (-118) vs. Azamat Murzakanov (-102): A light heavyweight battle between two hard-hitting contenders, with Rakic returning from injury to face the undefeated Murzakanov in a closely contested bout.
Daniel Vithlani has made strong picks for all these bouts, including a specific fighter he believes "will use a physicality and wrestling edge" to secure a massive victory. His full analysis and detailed picks for the entire UFC 321 card are available exclusively at SportsLine.
For comprehensive insights into who will emerge victorious at UFC 321: Aspinall vs. Gane, including specific fight endings and in-depth analysis from the expert who is up over $1,500 on his UFC main-card picks, visit SportsLine now.
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